Abstract 3934: Determination of the PI3Kα selective inhibitor alpelisib mechanism of action and efficacy in ER+/ PIK3CA mutant breast cancer preclinical models
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DOI: 10.1158/1538-7445.am2018-3934
Abstract: Over the past years, a key focus has been on identifying inhibitors against components of pathways that drive tumor cell proliferation, survival, and metastasis such as the PI3K/mTOR pathway, known to be implicated in many… read more here.
Keywords: breast cancer; pik3ca; mutant breast; cancer ... See more keywords