Defective interaction of mutant calreticulin and SOCE in megakaryocytes from patients withmyeloproliferative neoplasms.
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DOI: 10.1182/blood.2019001103
Abstract: About one fourth of patients with essential thrombocythemia or primary myelofibrosis carry a somatic mutation of CALR, the gene encoding for calreticulin. A 52-bp deletion (Type I mutation) and a 5-bp insertion (Type II mutation)… read more here.
Keywords: mutant calreticulin; calreticulin; megakaryocytes patients; myeloproliferative neoplasms ... See more keywords