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Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14820
Abstract: Mutations in the E3 ubiquitin ligase CBL, found in several myeloid neoplasms, lead to decreased ubiquitin ligase activity. In murine systems, these mutations are associated with cytokine‐independent proliferation, thought to result from the activation of…
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Keywords:
mutant cbl;
leukaemia cells;
kinase;
inhibition ... See more keywords