Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys
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DOI: 10.1016/j.cell.2017.04.035
Abstract: Gene-editing technologies have made it feasible to create nonhuman primate models for human genetic disorders. Here, we report detailed genotypes and phenotypes of TALEN-edited MECP2 mutant cynomolgus monkeys serving as a model for a neurodevelopmental… read more here.
Keywords: talen edited; cynomolgus monkeys; rett syndrome; mutant cynomolgus ... See more keywords