Serial enrichment of heteroduplex DNA using a MutS‐magnetic bead system
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology Journal"
DOI: 10.1002/biot.202200323
Abstract: Numerous applications in molecular biology and genomics require characterization of mutant DNA molecules present at low levels within a larger sample of non‐mutant DNA. This is often achieved either by selectively amplifying mutant DNA, or… read more here.
Keywords: system; dna; enrichment; mutant dna ... See more keywords
Association Of Plasma And Urinary Mutant DNA With Clinical Outcomes In Muscle Invasive Bladder Cancer
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DOI: 10.1038/s41598-017-05623-3
Abstract: Muscle Invasive Bladder Cancer (MIBC) has a poor prognosis. Whilst patients can achieve a 6% improvement in overall survival with Neo-Adjuvant Chemotherapy (NAC), many do not respond. Body fluid mutant DNA (mutDNA) may allow non-invasive… read more here.
Keywords: bladder cancer; invasive bladder; mutant dna; muscle invasive ... See more keywords
Secretion of Mutant DNA and mRNA by the Exosomes of Breast Cancer Cells
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DOI: 10.3390/molecules26092499
Abstract: Exosomes are the small vesicles that are secreted by different types of normal and tumour cells and can incorporate and transfer their cargo to the recipient cells. The main goal of the present work was… read more here.
Keywords: cancer cells; breast cancer; mutant dna; dna ... See more keywords