Dependency of Spliceosomal Mutant MDS on Innate Immune Signaling
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DOI: 10.1182/blood-2018-99-111552
Abstract: Mutations in genes encoding RNA splicing factors constitute the most common class of genetic alterations in patients with myelodysplastic syndromes (MDS). These occur as heterozygous point mutations at specific amino acid residues in SF3B1, SRSF2,… read more here.
Keywords: sf3b1; map3k7; figure; sf3b1 mutant ... See more keywords