Articles with "mutant medullary" as a keyword



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LIBRETTO-531: a phase III study of selpercatinib in multikinase inhibitor-naïve RET-mutant medullary thyroid cancer.

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Published in 2022 at "Future oncology"

DOI: 10.2217/fon-2022-0657

Abstract: Selpercatinib is a first-in-class, highly selective and potent, central nervous system-active RET kinase inhibitor. In the phase I/II trial, selpercatinib demonstrated clinically meaningful antitumor activity with manageable toxicity in heavily pre-treated and treatment-naive patients with… read more here.

Keywords: mutant medullary; ret mutant; phase; inhibitor ... See more keywords