The mutant neoantigen specific T cell is a personalized immunotherapy in refractory solid tumour
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz253.054
Abstract: Abstract Background Immune checkpoint inhibitors are an important therapy. However, their essence is nonspecific and efficiency of single usage is not satisfactory. The mutant neoantigen specific T (Nas-T) cell, as an adoptive cell treatment, is… read more here.
Keywords: neoantigen; neoantigen specific; cell personalized; personalized immunotherapy ... See more keywords
Abstract LB132: In silico mutant neoantigen prediction - a promising avenue for target identification in human adrenocortical carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb132
Abstract: Introduction: Adrenocortical carcinoma (ACC) is one of the most aggressive endocrine malignancies and confers a poor prognosis in advanced stages. Effective treatments are lacking. The results of immune checkpoint inhibition were disappointing with few responders… read more here.
Keywords: adrenocortical carcinoma; silico; mutant neoantigen; target identification ... See more keywords