Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories
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DOI: 10.1038/ncomms13671
Abstract: Germline mutations in the BRCA2 tumour suppressor are associated with both an increased lifetime risk of developing prostate cancer (PCa) and increased risk of aggressive disease. To understand this aggression, here we profile the genomes… read more here.
Keywords: brca2 mutations; germline brca2; mutant pca; brca2 ... See more keywords