Cushing's syndrome mutant PKAL205R exhibits altered substrate specificity
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12562
Abstract: The PKAL205R hotspot mutation has been implicated in Cushing's syndrome through hyperactive gain‐of‐function PKA signaling; however, its influence on substrate specificity has not been investigated. Here, we employ the Proteomic Peptide Library (ProPeL) approach to… read more here.
Keywords: mutant pkal205r; cushing syndrome; substrate specificity; syndrome mutant ... See more keywords