Articles with "mutant proinsulin" as a keyword



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Peptide Model of the Mutant Proinsulin Syndrome. I. Design and Clinical Correlation

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Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.821069

Abstract: The mutant proinsulin syndrome is a monogenic cause of diabetes mellitus due to toxic misfolding of insulin’s biosynthetic precursor. Also designated mutant INS-gene induced diabetes of the young (MIDY), this syndrome defines molecular determinants of… read more here.

Keywords: proinsulin syndrome; mutant proinsulin; peptide model; model ... See more keywords