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Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.821069
Abstract: The mutant proinsulin syndrome is a monogenic cause of diabetes mellitus due to toxic misfolding of insulin’s biosynthetic precursor. Also designated mutant INS-gene induced diabetes of the young (MIDY), this syndrome defines molecular determinants of…
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Keywords:
proinsulin syndrome;
mutant proinsulin;
peptide model;
model ... See more keywords