Role of Obesity-Induced Mitochondrial Dysfunction and Inflammation in Neuropathology
Sign Up to like & getrecommendations! Published in 2025 at "Physiology"
DOI: 10.1152/physiol.2025.40.s1.0472
Abstract: Study objective: Chronic inflammation induced by obesity is suggested to be the underlying mechanism that drives pathological alterations within the body, gradually leading to multiple tissues becoming insulin resistant and developing a dysfunctional energy metabolism.… read more here.
Keywords: brain; physiology; lepr mutant; obesity ... See more keywords
Down-Regulation of Astrocytic Kir4.1 Channels during the Audiogenic Epileptogenesis in Leucine-Rich Glioma-Inactivated 1 (Lgi1) Mutant Rats
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20051013
Abstract: The dysfunction of astrocytic inwardly rectifying potassium (Kir) 4.1 channels, which mediate the spatial potassium-buffering function of astrocytes, is known to be involved in the development of epilepsy. Here, we analyzed the Kir4.1 expressional changes… read more here.
Keywords: astrocytic kir4; epileptogenesis; mutant rats; kir4 channels ... See more keywords