High frequencies of circulating memory T cells specific for calreticulin exon 9 mutations in healthy individuals
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DOI: 10.1038/s41408-018-0166-4
Abstract: Mutations in exon 9 of the calreticulin gene (CALR) frequently occur in patients with chronic myeloproliferative neoplasms (MPN). Patients exhibit spontaneous cellular immune responses to epitopes derived from the mutant CALR C-terminus, and CALR-mutant-specific T… read more here.
Keywords: healthy individuals; memory cells; calr mutant; calr ... See more keywords