Abstract B04: High-level expression of oncogenic KRAS is required to transform LKB1 mutant tissue in vivo
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DOI: 10.1158/1557-3125.ras18-b04
Abstract: Although activating mutations in the GTPase KRAS are oncogenic and implicated in various malignancies, mutations in KRAS alone are inefficient to transform epithelia. In lung adenocarcinoma, KRAS mutations occur at high frequency and co-segregate with… read more here.
Keywords: oncogenic kras; level expression; tissue; lkb1 ... See more keywords