In vitro characterization of the intramelanosomal domain of human recombinant TYRP1 and its oculocutaneous albinism type 3‐related mutant variants
Sign Up to like & getrecommendations! Published in 2022 at "Protein Science"
DOI: 10.1002/pro.4518
Abstract: Tyrosinase related protein 1 (TYRP1) is the most abundant melanosomal protein of the melanocyte, where plays an important role in the synthesis of eumelanin, possibly catalyzing the oxidation of 5,6‐dihydroxyindole‐2‐carboxylic acid to 5,6‐quinone‐2‐carboxylic acid. Mutations… read more here.
Keywords: tyrp1; domain; intramelanosomal domain; oculocutaneous albinism ... See more keywords
Nucleic Acid Hybridization-Based Noise Suppression for Ultraselective Multiplexed Amplification of Mutant Variants.
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DOI: 10.1002/smll.202006370
Abstract: The analysis of mutant nucleic acid (NA) variants can provide crucial clinical and biological insights for many diseases. Yet, existing analysis techniques are generally constrained by nonspecific "noise" signals from excessive wildtype background sequences, especially… read more here.
Keywords: hybridization; ultraselective multiplexed; mutant variants; hybridization based ... See more keywords
Emergence of European and North American mutant variants of SARS‐CoV‐2 in Southeast Asia
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DOI: 10.1111/tbed.13748
Abstract: Abstract The SARS‐CoV‐2 coronavirus is responsible for the current COVID‐19 pandemic, with an ongoing toll of over 5 million infections and 333 thousand deaths worldwide within the first 5 months. Insight into the phylodynamics and… read more here.
Keywords: european north; southeast asia; north american; sars cov ... See more keywords
Characterization of Cauliflower OR Mutant Variants
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DOI: 10.3389/fpls.2019.01716
Abstract: Cauliflower Orange (Or) mutant is characterized by high level of β-carotene in its curd. Or mutation affects the OR protein that was shown to be involved in the posttranslational control of phytoene synthase (PSY), a… read more here.
Keywords: boor; boor variants; cauliflower mutant; cauliflower ... See more keywords