Immune Checkpoint Blockade Enhances Mutated Calreticulin-Induced T Cell Immunity in Myeloproliferative Neoplasms
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DOI: 10.1182/blood.v130.suppl_1.384.384
Abstract: Somatic mutations in the calreticulin (CALR) gene are key drivers of cellular transformation in myeloproliferative neoplasms (MPN) and are the second most common driver mutations in essential thrombocythemia (ET) and myelofibrosis (MF) patients. Each CALR… read more here.
Keywords: cell responses; mpn; mpn patients; cell ... See more keywords