MicroRNA Expression in KRAS- and BRAF-mutated Colorectal Cancers.
Sign Up to like & getrecommendations! Published in 2018 at "Anticancer research"
DOI: 10.21873/anticanres.12272
Abstract: BACKGROUND/AIM KRAS and BRAF are two genes commonly mutated in colorectal cancer (CRC). Even though BRAF is a downstream target of KRAS in the MAPK signalling pathway, KRAS- and BRAF-mutated CRCs are found to display… read more here.
Keywords: kras braf; mir; braf mutated; mutated colorectal ... See more keywords
The Therapeutic Landscape for KRAS-Mutated Colorectal Cancers
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DOI: 10.3390/cancers15082375
Abstract: Simple Summary More than a third of all colorectal cancers have a KRAS mutation. The complex biology of these cancers has challenged the development of direct targeting inhibitors. Substantial leaps have been made in recent… read more here.
Keywords: colorectal cancers; cancers therapeutic; development; mutated colorectal ... See more keywords