Characterization of a mutated KCNJ5 gene, G387R, in unilateral primary aldosteronism.
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DOI: 10.1530/jme-20-0282
Abstract: Somatic mutation in the KCNJ5 gene is a common driver of autonomous aldosterone overproduction in aldosterone-producing adenomas (APA). KCNJ5 mutations contribute to a loss of potassium selectivity and an inward Na+ current could be detected… read more here.
Keywords: kcnj5; mutated kcnj5; kcnj5 gene; kcnj5 mutations ... See more keywords