Genomic Features of Exceptional Response in Vemurafenib ± Cobimetinib–treated Patients with BRAFV600-mutated Metastatic Melanoma
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-18-0720
Abstract: Purpose: Previous investigations identified transcriptional signatures associated with innate resistance to anti–programmed cell death protein 1 therapy in melanoma. This analysis aimed to increase understanding of the role of baseline genetic features in the variability… read more here.
Keywords: response; brafv600 mutated; progression; tumors patients ... See more keywords
Real-world data of a cohort of patients with EGFR mutated metastatic non-small cell lung cancer (NSCLC), follow up of 52 months in Fundación Santa Fe de Bogota.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e19287
Abstract: e19287Background: In Colombia, clinical information about EGFR mutated metastatic NSCLC is deficient. The goal of this study is to describe the characteristics and outcomes of a cohort of patients ... read more here.
Keywords: egfr mutated; real world; data cohort; cohort patients ... See more keywords
BRAF V600-Mutated Metastatic Melanoma and Targeted Therapy Resistance: An Update of the Current Knowledge
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15092607
Abstract: Simple Summary Metastatic melanoma is the most lethal skin cancer due to its high metastatic potential and resistance to treatment. The advent of targeted therapies has improved patient management. However, due to the emergence of… read more here.
Keywords: targeted therapies; braf v600; mutated metastatic; melanoma ... See more keywords