Mutation-Derived Neoantigens for Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01856
Abstract: Mutation-derived neoantigens distinguish tumor from normal cells. T cells can sense the HLA-presented mutations, recognize tumor cells as non-self and destroy them. Therapeutically, immunotherapy antibodies can increase the virulence of the immune system by increasing… read more here.
Keywords: mutation derived; derived neoantigens; mutated proteins; neoantigens cancer ... See more keywords
In-Silico Investigation of Effects of Single-Nucleotide Polymorphisms in PCOS-Associated CYP11A1 Gene on Mutated Proteins
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13071231
Abstract: Polycystic ovary syndrome (PCOS) is a reproductive disorder with multiple etiologies, mainly characterized by the excess production of androgens. It is equally contributed to by genes and environment. The CYP11A1 gene is imperative for steroidogenesis,… read more here.
Keywords: mutated proteins; nucleotide polymorphisms; cyp11a1 gene; single nucleotide ... See more keywords