Self-Internal-Reference Probe System for Control-Free Quantification of Mutation Abundance.
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DOI: 10.1021/acs.analchem.1c02877
Abstract: Gene mutations are important biomarkers for the diagnosis, classification, monitoring, and prognosis evaluation of cancers and genetic diseases. Both personalized cancer treatment and noninvasive prenatal testing require methods to accurately determine the abundance of mutation.… read more here.
Keywords: system; probe; mutation abundance; internal reference ... See more keywords