A Single Point Mutation Blocks the Entrance of Ligands to the Cannabinoid CB2 Receptor via the Lipid Bilayer
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DOI: 10.1021/acs.jcim.2c00865
Abstract: Molecular dynamic (MD) simulations have become a common tool to study the pathway of ligand entry to the orthosteric binding site of G protein-coupled receptors. Here, we have combined MD simulations and site-directed mutagenesis to… read more here.
Keywords: cannabinoid cb2; cb2 receptor; mutation blocks; receptor ... See more keywords