Effect of the Combination of Trabectedin and Pegylated Liposomal Doxorubicin in a BRCA2 Mutation Carrier with Recurrent Platinum-Sensitive Ovarian Cancer
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DOI: 10.1159/000475707
Abstract: Introduction: The current standard of care for ovarian cancer is optimal cytoreduction with adjuvant chemotherapy based on a platinum/taxane combination. Although the response rate to this therapy is high, most patients ultimately relapse. Response to… read more here.
Keywords: chemotherapy; platinum; ovarian cancer; brca2 mutation ... See more keywords
Cervical artery dissection and iliac artery aneurysm in an SMAD-4 mutation carrier
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DOI: 10.1212/nxg.0000000000000191
Abstract: Cervical artery dissection is an important cause of stroke, especially in younger individuals. Most cases appear to be sporadic, but rare monogenic conditions can cause dissection, such as vascular Ehlers-Danlos syndrome.1 The wider use of… read more here.
Keywords: artery; smad mutation; cervical artery; dissection ... See more keywords