Articles with "mutation dependent" as a keyword



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CSIG-24. GABP LINKS AMPK SIGNALING TO TERT REGULATION IN A TERT PROMOTER MUTATION DEPENDENT MANNER

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Published in 2019 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noz175.194

Abstract: Over 90% of human tumors achieve immortality by reactivating telomerase reverse transcriptase (TERT), the catalytic subunit of telomerase. Two mutually exclusive, heterozygous mutations that activate the TERT promoter (TERTp) occur in a wide range of… read more here.

Keywords: tert; promoter mutation; tert promoter; mutation dependent ... See more keywords