Mutation-Derived Neoantigens for Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01856
Abstract: Mutation-derived neoantigens distinguish tumor from normal cells. T cells can sense the HLA-presented mutations, recognize tumor cells as non-self and destroy them. Therapeutically, immunotherapy antibodies can increase the virulence of the immune system by increasing… read more here.
Keywords: mutation derived; derived neoantigens; mutated proteins; neoantigens cancer ... See more keywords
A Somatic Mutation-Derived LncRNA Signature of Genomic Instability Predicts Prognosis for Patients With Liver Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Surgery"
DOI: 10.3389/fsurg.2021.724792
Abstract: Background: Genomic instability is considered as one of the hallmarks of hepatocellular carcinoma (HCC) and poses a significant challenge to the clinical treatment. The emerging evidence has revealed the roles of long non-coding RNAs (lncRNAs)… read more here.
Keywords: genomic instability; mutation derived; lncrna signature; somatic mutation ... See more keywords