Dangerous Liaisons between Tet2 Mutation, Inflammatory Monocytes, and Leukemogenesis.
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DOI: 10.1158/2159-8290.cd-22-0846
Abstract: Transgenic knockin mice expressing a common loss-of-function mutation in human TET2 exhibit aging-related accelerated myeloid leukemia development and skewing of myelopoiesis toward the production of proinflammatory MHC-IIhi monocytes that may contribute to disease. See related… read more here.
Keywords: dangerous liaisons; inflammatory monocytes; liaisons tet2; tet2 mutation ... See more keywords