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   Articles with "mutation profiles" as a keyword



BnpC: Bayesian non-parametric clustering of single-cell mutation profiles

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recommendations! Published in 2020 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btaa599

Abstract: Abstract Motivation The high resolution of single-cell DNA sequencing (scDNA-seq) offers great potential to resolve intratumor heterogeneity (ITH) by distinguishing clonal populations based on their mutation profiles. However, the increasing size of scDNA-seq datasets and… read more here.

Keywords: single cell; mutation profiles; scdna seq; non parametric ... See more keywords

Drug resistance mutations and phylogenetic analysis of HIV-1 subtypes B and F from mothers and children with vertical transmission

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recommendations! Published in 2025 at "BMC Infectious Diseases"

DOI: 10.1186/s12879-025-11230-9

Abstract: This study aimed to describe the transmission of drug-resistant HIV-1 variants and phylogenetic characterisation of viral strains in mother–child pairs from the cities of Recife and São Luís, located in the Northeast region of Brazil,… read more here.

Keywords: transmission; resistance; hiv; drug ... See more keywords

Clinical outcomes of women with ovarian metastases of colorectal cancer treated with oophorectomy with respect to their somatic mutation profiles

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recommendations! Published in 2018 at "Oncotarget"

DOI: 10.18632/oncotarget.24735

Abstract: We clarified the clinical prevalence of ovarian metastases from colorectal cancers (CRCs) in 296 female patients with CRC and evaluated clinical outcomes with relation to their mutational profiles, such as BRAF/KRAS mutation and microsatellite instability… read more here.

Keywords: ovarian metastases; clinical outcomes; metastases colorectal; mutation profiles ... See more keywords

Somatic Mutation Profiles Revealed by Next Generation Sequencing (NGS) in 39 Chinese Hepatocellular Carcinoma Patients

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recommendations! Published in 2022 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2021.800679

Abstract: The features and significance of somatic mutation profiles in hepatocellular carcinoma (HCC) have not been completely elucidated to date. In this study, 39 tumor specimens from HCC patients were collected for gene variation analysis by… read more here.

Keywords: hepatocellular carcinoma; somatic mutation; mutation profiles; next generation ... See more keywords

Mutation Profiles of Ovarian Seromucinous Borderline Tumors in Japanese Patients

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recommendations! Published in 2022 at "Current Oncology"

DOI: 10.3390/curroncol29050294

Abstract: Ovarian seromucinous tumors (SMBTs) are relatively rare, and their carcinogenesis is largely unknown. In this study, the molecular features of SMBTs in Japan are assessed. DNA was extracted from microdissected paraffin-embedded sections from 23 SMBT… read more here.

Keywords: ovarian seromucinous; kras braf; braf pik3ca; loss ... See more keywords