Structural destabilization of tropomyosin induced by the cardiomyopathyâlinked mutation R21H
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DOI: 10.1002/pro.3341
Abstract: The missense mutation R21H in striated muscle tropomyosin is associated with hypertrophic cardiomyopathy, a genetic cardiac disease and a leading cause of sudden cardiac death in young people. Tropomyosin adopts conformation of a coiled coil… read more here.
Keywords: tm1a1 28zip; structural destabilization; tropomyosin; mutation r21h ... See more keywords