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Published in 2019 at "Journal of mathematical biology"
DOI: 10.1007/s00285-019-01430-8
Abstract: The transition distribution of a sample taken from a Wright-Fisher diffusion with general small mutation rates is found using a coalescent approach. The approximation is equivalent to having at most one mutation in the coalescent…
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Keywords:
wright fisher;
fisher diffusion;
mutation rates;
mutation ... See more keywords
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Published in 2019 at "International Journal of Legal Medicine"
DOI: 10.1007/s00414-019-02047-8
Abstract: As a supplementary tool in forensic cases, X chromosomal short tandem repeats (X-STRs) might bridge large pedigree gaps and bring inspiration to forensic practices for the special mode of inheritance. To standardize the application of…
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Keywords:
population beijing;
han chinese;
chinese population;
population ... See more keywords
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Published in 2019 at "Metabolomics"
DOI: 10.1007/s11306-019-1573-7
Abstract: The color variations of ornamental flowers are often generated by ion-beam and gamma irradiation mutagenesis. However, mutation rates differ significantly even among cultivars of the same species, resulting in high cost and intensive labor for…
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Keywords:
color;
metabolome based;
flower color;
mutation rates ... See more keywords
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Published in 2017 at "Bulletin of Mathematical Biology"
DOI: 10.1007/s11538-017-0247-8
Abstract: In around 1943, while writing a classic paper with Luria, Delbrück envisioned two kinds of mutation rates: One was expressed as mutations per bacterium per unit time, the other as mutations per bacterium per division…
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Keywords:
definition mutation;
mutation rates;
mutation;
mutation rate ... See more keywords
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Published in 2018 at "Current Biology"
DOI: 10.1016/j.cub.2018.08.050
Abstract: Mutation rates vary between species across several orders of magnitude, with larger organisms having the highest per-generation mutation rates. Hypotheses for this pattern typically invoke physiological or population-genetic constraints imposed on the molecular machinery preventing…
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Keywords:
reproductive longevity;
generation;
rates primates;
mutation rates ... See more keywords
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Published in 2019 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.8b00681
Abstract: Scop3D is a tool that automatically annotates protein structure with sequence conservation starting from a set of protein sequence variants. We present a complete upgrade and rewrite of Scop3D. We have included a DNA module…
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Keywords:
visualization mutation;
protein structure;
online visualization;
scop3d online ... See more keywords
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Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-66867-0
Abstract: Ageing may be due to mutation accumulation across the lifespan, leading to tissue dysfunction, disease, and death. We tested whether germline autosomal mutation rates in young adults predict their remaining survival, and, for women, their…
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Keywords:
germline mutation;
mutation;
mutation accumulation;
mutation rates ... See more keywords
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Published in 2022 at "Annals of Human Biology"
DOI: 10.1080/03014460.2022.2105397
Abstract: Abstract Background Short tandem repeats (STRs) are genetic markers frequently used for human identification and paternity testing. They are highly mutable, which may occasionally lead to inconsistencies between the genotypes of parents and their children.…
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Keywords:
mutation rates;
slovak population;
str markers;
mutation ... See more keywords
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Published in 2021 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evab241
Abstract: Abstract Mutations that cause structural variation are important sources of genetic variation upon which other evolutionary forces can act, however, they are difficult to observe and therefore few direct estimates of their rate and spectrum…
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Keywords:
rate;
intraspecific variation;
mutation;
mutation rates ... See more keywords
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Published in 2021 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evab257
Abstract: Abstract How microbes adapt to a novel environment is a central question in evolutionary biology. Although adaptive evolution must be fueled by beneficial mutations, whether higher mutation rates facilitate the rate of adaptive evolution remains…
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Keywords:
evolution;
biology;
novel environment;
mutation rates ... See more keywords
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Published in 2019 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evz056
Abstract: Abstract Chlorarachniophyte and cryptophyte algae are unique among plastid-containing species in that they have a nucleomorph genome: a compact, highly reduced nuclear genome from a photosynthetic eukaryotic endosymbiont. Despite their independent origins, the nucleomorph genomes…
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Keywords:
bearing algae;
nucleomorph bearing;
rates nucleomorph;
relative mutation ... See more keywords