Radiomics based on dual‐layer spectral detector CT for predicting EGFR mutation status in non‐small cell lung cancer
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Applied Clinical Medical Physics"
DOI: 10.1002/acm2.14616
Abstract: Abstract Objective To explore the value of dual‐layer spectral computed tomography (DLCT)‐based radiomics for predicting epidermal growth factor receptor (EGFR) mutation status in patients with non‐small cell lung cancer (NSCLC). Methods DLCT images and clinical… read more here.
Keywords: mutation status; egfr mutation; layer spectral; dual layer ... See more keywords
A radiomics‐based nomogram may be useful for predicting telomerase reverse transcriptase promoter mutation status in adult glioblastoma
Sign Up to like & getrecommendations! Published in 2024 at "Brain and Behavior"
DOI: 10.1002/brb3.3528
Abstract: As a crucial diagnostic and prognostic biomarker, telomerase reverse transcriptase (TERT) promoter mutation holds immense significance for personalized treatment of patients with glioblastoma (GBM). In this study, we developed a radiomics nomogram to determine the… read more here.
Keywords: telomerase reverse; promoter; mutation status; reverse transcriptase ... See more keywords
Combination of KIT and FLT3‐ITD mutation status with minimal residual disease levels guides treatment strategy for adult patients with inv(16) acute myeloid leukemia in first complete remission
Sign Up to like & getrecommendations! Published in 2022 at "Hematological Oncology"
DOI: 10.1002/hon.3015
Abstract: Although several studies have investigated the benefits of allogeneic hematopoietic stem cell transplantation (allo‐HSCT) for patients with inv (16) acute myeloid leukemia (AML) in first complete remission (CR1) individually stratified by KIT or FMS‐like tyrosine… read more here.
Keywords: combination; flt3 itd; allo hsct; mutation status ... See more keywords
Association between squamous cell carcinoma antigen level and EGFR mutation status in Chinese lung adenocarcinoma patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24613
Abstract: To investigate the association between squamous cell carcinoma antigen (SCCAg) level and epidermal growth factor receptor (EGFR) mutation status in Chinese lung adenocarcinoma patients. read more here.
Keywords: cell carcinoma; mutation status; squamous cell; carcinoma antigen ... See more keywords
Identification of IDH and TERTp mutation status using 1H‐MRS in 112 hemispheric diffuse gliomas
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.26964
Abstract: There is a growing interest in noninvasively defining molecular subsets of hemispheric diffuse gliomas based on the isocitrate dehydrogenase (IDH) and telomerase reverse transcriptase gene promoter (TERTp) mutation status, which correspond to distinct tumor entities,… read more here.
Keywords: mutation status; hemispheric diffuse; tertp mutation; diffuse gliomas ... See more keywords
Enhancing predictability of IDH mutation status in glioma patients at initial diagnosis: a comparative analysis of radiomics from MRI, [18F]FET PET, and TSPO PET
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-024-06654-5
Abstract: According to the World Health Organization classification for tumors of the central nervous system, mutation status of the isocitrate dehydrogenase (IDH) genes has become a major diagnostic discriminator for gliomas. Therefore, imaging-based prediction of IDH… read more here.
Keywords: mutation status; 18f fet; idh mutation; fet pet ... See more keywords
Radiomics signature of brain metastasis: prediction of EGFR mutation status
Sign Up to like & getrecommendations! Published in 2021 at "European Radiology"
DOI: 10.1007/s00330-020-07614-x
Abstract: To predict epidermal growth factor receptor (EGFR) mutation status in lung adenocarcinoma using MR-based radiomics signature of brain metastasis and explore the optimal MR sequence for prediction. Data from 52 patients with brain metastasis from… read more here.
Keywords: mutation status; radiomics signature; egfr mutation; signature ... See more keywords
Predictive models for patients with lung carcinomas to identify EGFR mutation status via an artificial neural network based on multiple clinical information
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-019-03103-x
Abstract: Purpose Epidermal growth factor receptor (EGFR) mutation testing has several limitations. Therefore, we built predictive models to determine the EGFR mutation status of patients and guide therapeutic decision-making. Methods We collected data from 320 patients… read more here.
Keywords: model; model auroc; egfr mutation; mutation status ... See more keywords
Clinical assessment of the GNAS mutation status in patients with intraductal papillary mucinous neoplasm of the pancreas
Sign Up to like & getrecommendations! Published in 2019 at "Surgery Today"
DOI: 10.1007/s00595-019-01797-7
Abstract: Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is characterized by cystic dilation of the pancreatic duct, caused by mucin hypersecretion, with slow progression via the adenoma–carcinoma sequence mechanism. Mutation of GNAS at codon 201… read more here.
Keywords: papillary mucinous; mutation status; gnas mutation; intraductal papillary ... See more keywords
Impact of carbamazepine on SMARCA4 (BRG1) expression in colorectal cancer: modulation by KRAS mutation status
Sign Up to like & getrecommendations! Published in 2024 at "Investigational New Drugs"
DOI: 10.1007/s10637-024-01418-2
Abstract: SMARCA4 is a gene traditionally considered a tumor suppressor. Recent research has however found that SMARCA4 likely promotes cancer growth and is a good target for cancer treatment. The drug carbamazepine, an autophagy inducer, was… read more here.
Keywords: colorectal cancer; mutation status; cancer; carbamazepine ... See more keywords
The Long-To-Short-Axis Ratio and Multifocality are Associated With TP53 Mutation Status in Surgically Resected Hepatocellular Carcinomas.
Sign Up to like & getrecommendations! Published in 2018 at "Academic radiology"
DOI: 10.1016/j.acra.2018.04.021
Abstract: RATIONALE AND OBJECTIVES In hepatocellular carcinoma (HCC), the tumor protein 53 (TP53) gene is frequently mutated and the mutations have been associated with poor prognosis. We aim to retrospectively identify the relationship between TP53 mutation… read more here.
Keywords: tp53 mutation; mutation status; ratio; multifocality ... See more keywords