Characterization of KRAS Mutation Subtypes in Non–small Cell Lung Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-21-0201
Abstract: KRAS is the most commonly mutated oncogene in NSCLC and development of direct KRAS inhibitors has renewed interest in this molecular variant. Different KRAS mutations may represent a unique biologic context with different prognostic and… read more here.
Keywords: mutation subtypes; kras mutation; cancer; cell ... See more keywords
Three-dimensional topological radiogenomics of epidermal growth factor receptor Del19 and L858R mutation subtypes on computed tomography images of lung cancer patients.
Sign Up to like & getrecommendations! Published in 2023 at "Computer methods and programs in biomedicine"
DOI: 10.2139/ssrn.4093528
Abstract: OBJECTIVES To elucidate a novel radiogenomics approach using three-dimensional (3D) topologically invariant Betti numbers (BNs) for topological characterization of epidermal growth factor receptor (EGFR) Del19 and L858R mutation subtypes. METHODS In total, 154 patients (wild-type… read more here.
Keywords: epidermal growth; three dimensional; l858r mutation; mutation ... See more keywords
Isocitrate dehydrogenase 1 mutation subtypes at site 132 and their translational potential in glioma
Sign Up to like & getrecommendations! Published in 2018 at "CNS Oncology"
DOI: 10.2217/cns-2017-0019
Abstract: In recent years, de novo missense structural mutations in the IDH1 gene of arginine at site 132 (R132) have become a standard for diagnostication and prognostication in glioma management. As our clinical understanding of this… read more here.
Keywords: glioma; mutation subtypes; site 132; translational potential ... See more keywords
Comprehensive analysis of prediction of the EGFR mutation and subtypes based on the spinal metastasis from primary lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1154327
Abstract: Purpose To investigate the use of multiparameter MRI-based radiomics in the in-depth prediction of epidermal growth factor receptor (EGFR) mutation and subtypes based on the spinal metastasis in patients with primary lung adenocarcinoma. Methods A… read more here.
Keywords: metastasis; egfr mutation; prediction; mutation subtypes ... See more keywords