Significance of KRAS mutation testing in biliary brushing cytology specimens: A 10‐year retrospective review
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22579
Abstract: Biliary strictures can be caused by benign and malignant conditions. A biliary duct brushing diagnosis can be challenging because of low cellularity and overlapping morphology among different entities, leading to a variable reported sensitivity. This… read more here.
Keywords: significance kras; mutation testing; testing biliary; cytology ... See more keywords
Age‐dependent performance of BRAF mutation testing in Lynch syndrome diagnostics
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33273
Abstract: BRAF V600E mutations have been reported as a marker of sporadic microsatellite instability (MSI) colorectal cancer (CRC). Current international diagnostic guidelines recommend BRAF mutation testing in MSI CRC patients to predict low risk of Lynch… read more here.
Keywords: age; braf testing; braf; mutation testing ... See more keywords
Towards practical application of mutation testing in industry — Traditional versus extreme mutation testing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Software: Evolution and Process"
DOI: 10.1002/smr.2450
Abstract: Mutation testing is a technique that changes code instructions to assess the quality of automated software tests. Industry has not broadly adopted the technique because execution and analysis times are too long and not considered… read more here.
Keywords: software; towards practical; mutation testing; extreme mutation ... See more keywords
BRAF mutation testing in melanoma: results from a German observational multicenter study
Sign Up to like & getrecommendations! Published in 2018 at "Virchows Archiv"
DOI: 10.1007/s00428-018-2480-4
Abstract: Quality control of BRAF mutation testing methods used in routine practice is crucial for optimal treatment selection. In this prospective study, we assessed the impact of patient/sample characteristics on BRAF mutation testing results in patients… read more here.
Keywords: sample; mutation testing; pathology; study ... See more keywords
How effective are mutation testing tools? An empirical analysis of Java mutation testing tools with manual analysis and real faults
Sign Up to like & getrecommendations! Published in 2017 at "Empirical Software Engineering"
DOI: 10.1007/s10664-017-9582-5
Abstract: Mutation analysis is a well-studied, fault-based testing technique. It requires testers to design tests based on a set of artificial defects. The defects help in performing testing activities by measuring the ratio that is revealed… read more here.
Keywords: testing tools; analysis; mutation testing; real faults ... See more keywords
EGFR Mutation Testing of non-squamous NSCLC: Impact and Uptake during Implementation of Testing Guidelines in a Population-Based Registry Cohort from Northern New Zealand
Sign Up to like & getrecommendations! Published in 2017 at "Targeted Oncology"
DOI: 10.1007/s11523-017-0515-4
Abstract: BackgroundSince 2013, clinical practice guidelines recommend EGFR mutation testing of non-squamous NSCLC to select advanced-stage patients for first-line treatment using EGFR-TKIs.ObjectiveWe aimed to determine population-based trends in the real-world uptake and impact in routine practice… read more here.
Keywords: egfr mutation; population based; mutation testing; population ... See more keywords
Utility of Cerebrospinal Fluid Cell-Free DNA in Patients with EGFR-Mutant Non-Small-Cell Lung Cancer with Leptomeningeal Metastasis
Sign Up to like & getrecommendations! Published in 2021 at "Targeted Oncology"
DOI: 10.1007/s11523-021-00791-9
Abstract: Leptomeningeal metastasis (LM) is a fatal complication of advanced non-small-cell lung cancer (NSCLC). The aim of this study was to evaluate the utility of cerebrospinal fluid (CSF) as a medium for epidermal growth factor receptor… read more here.
Keywords: egfr mutation; mutation testing; csf; cell ... See more keywords
Diagnostic and prognostic value of a 7-panel mutation testing in thyroid nodules with indeterminate cytology: the SWEETMAC study
Sign Up to like & getrecommendations! Published in 2020 at "Endocrine"
DOI: 10.1007/s12020-020-02411-4
Abstract: Purpose The aim of this prospective study (ClinicalTrials.gov: NCT01880203) was to evaluate the diagnostic and prognostic value of a 7-panel mutation testing in the aspirates of thyroid nodules with indeterminate cytology (IC). Methods Eligible patients… read more here.
Keywords: panel mutation; mutation testing; value; study ... See more keywords
Dealing with NSCLC EGFR mutation testing and treatment: a comprehensive review with an Italian real-world perspective.
Sign Up to like & getrecommendations! Published in 2021 at "Critical reviews in oncology/hematology"
DOI: 10.1016/j.critrevonc.2021.103300
Abstract: Since their discovery, relevant efforts have been made to optimize the detection approaches to EGFR mutations as well as the clinical management of EGFR-mutated NSCLC. The recent shift from single gene testing to novel comprehensive… read more here.
Keywords: egfr mutation; dealing nsclc; treatment; mutation testing ... See more keywords
Recommendations for a practical implementation of circulating tumor DNA mutation testing in metastatic non-small-cell lung cancer
Sign Up to like & getrecommendations! Published in 2022 at "ESMO Open"
DOI: 10.1016/j.esmoop.2022.100399
Abstract: Background Liquid biopsy (LB) is a rapidly evolving diagnostic tool for precision oncology that has recently found its way into routine practice as an adjunct to tissue biopsy (TB). The concept of LB refers to… read more here.
Keywords: circulating tumor; mutation testing; tumor dna; mutation ... See more keywords
Scalable Mutation Testing Using Predictive Analysis of Deep Learning Model
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Access"
DOI: 10.1109/access.2019.2950171
Abstract: Software testing plays a crucial role in ensuring the quality of software systems. Mutation testing is designed to measure the adequacy of test suites by detecting artificially induced software faults. Despite their potential, the expensive… read more here.
Keywords: mutation; analysis; mutation testing; deep learning ... See more keywords