A Single Mutation in the VP1 Gene of Enterovirus 71 Enhances Viral Binding to Heparan Sulfate and Impairs Viral Pathogenicity in Mice
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DOI: 10.3390/v12080883
Abstract: Enterovirus 71 (EV71) is the major causative pathogen of human hand, foot, and mouth disease (hHFMD) and has evolved to use various cellular receptors for infection. However, the relationship between receptor preference and EV71 virulence… read more here.
Keywords: ev71; enterovirus; heparan sulfate; mutation vp1 ... See more keywords