Mutational Evolution of Pseudomonas aeruginosa Resistance to Ribosome-Targeting Antibiotics
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DOI: 10.3389/fgene.2018.00451
Abstract: The present work examines the evolutionary trajectories of replicate Pseudomonas aeruginosa cultures in presence of the ribosome-targeting antibiotics tobramycin and tigecycline. It is known that large number of mutations across different genes – and therefore… read more here.
Keywords: pseudomonas aeruginosa; ribosome targeting; evolution; targeting antibiotics ... See more keywords
Mutational Evolution in Relapsed Diffuse Large B-Cell Lymphoma
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DOI: 10.3390/cancers10110459
Abstract: Current genomic models in diffuse large B-cell lymphoma (DLBCL) are based on single tumor biopsies, which might underestimate heterogeneity. Data on mutational evolution largely remains unknown. An exploratory study using whole exome sequencing on paired… read more here.
Keywords: evolution; large cell; mutational evolution; diffuse large ... See more keywords