Inferring the intrinsic mutational fitness landscape of influenzalike evolving antigens from temporally ordered sequence data.
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DOI: 10.1103/physreve.105.024401
Abstract: There still are no effective long-term protective vaccines against viruses that continuously evolve under immune pressure such as seasonal influenza, which has caused, and can cause, devastating epidemics in the human population. To find such… read more here.
Keywords: mutational fitness; fitness landscape; sequence; fitness ... See more keywords