Relaxed sequence constraints favor mutational freedom in idiosyncratic metazoan mitochondrial tRNAs
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DOI: 10.1038/s41467-020-14725-y
Abstract: Metazoan complexity and life-style depend on the bioenergetic potential of mitochondria. However, higher aerobic activity and genetic drift impose strong mutation pressure and risk of irreversible fitness decline in mitochondrial (mt)DNA-encoded genes. Bilaterian mitochondria-encoded tRNA… read more here.
Keywords: mitochondrial trnas; relaxed sequence; sequence constraints; mutational freedom ... See more keywords