Abstract LB-262: A somatic-mutational process in breast cancer genomes recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers
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DOI: 10.1158/1538-7445.am2017-lb-262
Abstract: Somatic rearrangements are a part of mutational landscape of human cancer genomes. We systematically investigated the distribution of the somatic rearrangements in 560 breast cancer genomes and highlight 33 rearrangement hotspots associated with a signature… read more here.
Keywords: susceptibility; breast; breast cancer; cancer ... See more keywords