Comparative study on the mutational profile of adenocarcinoma and squamous cell carcinoma predominant histologic subtypes in Chinese non‐small cell lung cancer patients
Sign Up to like & getrecommendations! Published in 2019 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.13208
Abstract: Distinction in the mutational profile between the common histological types, lung adenocarcinoma (LUAD) and squamous cell lung carcinoma (LUSC) has been well‐established. However, comprehensive mutation profiles of the predominant histological subtypes within LUAD and LUSC… read more here.
Keywords: squamous cell; cell; cell lung; mutational profile ... See more keywords
Mutational profile, outcomes, and impact of allogeneic hematopoietic stem cell transplantation in adult patients with acute myeloid leukemia and inconclusive cytogenetic analysis
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Haematology"
DOI: 10.1111/ejh.13940
Abstract: Inconclusive cytogenetic analysis (IC) at baseline has been reported as a predictor of poor prognosis in patients with acute myeloid leukemia (AML). The mutational profile in this group of patients, and its impact on outcomes… read more here.
Keywords: myeloid leukemia; cytogenetic analysis; acute myeloid; mutational profile ... See more keywords
Mutational profile in previously treated patients with chronic lymphocytic leukemia progression on acalabrutinib or ibrutinib
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood.2023023659
Abstract: Key Points • BTK C481S was most common in both groups; in the acalabrutinib arm, low-VAF T474I (9/47; 8 co-occurring with C481S) but no L528W was seen.• More patients receiving acalabrutinib acquired BTK mutations, though… read more here.
Keywords: patients chronic; profile previously; previously treated; treated patients ... See more keywords
Comprehensive immune and mutational profile of melanoma.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.5_suppl.182
Abstract: 182Background: The association between tumor mutational profiles and immune signatures has not been well-characterized. Methods: 306 melanoma samples were tested by NGS using a comprehensive cancer panel for mutational status and an immune response panel… read more here.
Keywords: melanoma; profile melanoma; immune mutational; mutational profile ... See more keywords
Mutational profile analysis and related outcomes in primary and metastatic pancreatic cancer (PC).
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.3_suppl.427
Abstract: 427Background: PC has not been well molecularly characterized and there is an unmet need in our understanding of the biological properties of PC. One previous study has found that the presence of C... read more here.
Keywords: primary metastatic; mutational profile; outcomes primary; analysis related ... See more keywords
Impact of Mutational Profile on the Management of Myeloproliferative Neoplasms: A Short Review of the Emerging Data
Sign Up to like & getrecommendations! Published in 2020 at "OncoTargets and therapy"
DOI: 10.2147/ott.s287944
Abstract: Abstract Philadelphia-chromosome negative myeloproliferative neoplasms (MPN) are a heterogeneous group of clonal hematopoietic stem cell disorders characterized by an increased risk of thrombosis and progression to acute myeloid leukemia. MPN are associated with driver mutations… read more here.
Keywords: myeloproliferative neoplasms; review; mutational profile; profile management ... See more keywords
Mutational Profile in Romanian Patients with Hemophilia A
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms25158366
Abstract: Hemophilia A (HA) is an X-linked recessive bleeding disorder caused by mutations in the F8 gene, resulting in deficient or dysfunctional factor VIII (FVIII). This study aimed to characterize the mutational profile of HA in… read more here.
Keywords: profile romanian; romanian patients; patients hemophilia; mutational profile ... See more keywords