A biobank for bladder cancer
Sign Up to like & getrecommendations! Published in 2018 at "Nature Cell Biology"
DOI: 10.1038/s41556-018-0114-3
Abstract: Diverse clinical outcomes in bladder cancers result from varying molecular profiles. Shen and colleagues generated a biobank of patient-derived bladder cancer organoids to study tumour heterogeneity, evolution and drug responses. Organoid lines were established from… read more here.
Keywords: bladder cancer; mutational profiles; biobank bladder; cancer organoids ... See more keywords
Paired comparisons of mutational profiles before and after brachytherapy in asian uveal melanoma patients
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-98084-8
Abstract: Uveal melanoma(UM) is the most common primary intraocular malignancy in adults. However, the incidence of UM in Asia is 10 to 20 times less than in Western populations. Therefore, for the first time, we report… read more here.
Keywords: mutational profiles; profiles brachytherapy; uveal melanoma; samples brachytherapy ... See more keywords
HPV+ Oropharyngeal Squamous Cell Carcinomas from patients with two tumors display synchrony of viral genomes yet discordant mutational profiles and signatures.
Sign Up to like & getrecommendations! Published in 2020 at "Carcinogenesis"
DOI: 10.1093/carcin/bgaa111
Abstract: Human Papillomavirus (HPV) positive oropharyngeal squamous cell carcinoma (HPV+OPSCC) is increasing in prevalence in the United States, as are cases of patients with multiple HPV+OPSCCs (mHPV+OPSCC). mHPV+OPSCCs present a unique opportunity to examine HPV+OPSCC mutation… read more here.
Keywords: mutational profiles; hpv opsccs; squamous cell; patients two ... See more keywords
Mutational profiles and clinical outcomes in metastatic colorectal carcinoma patients with different metastases sites.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e16020
Abstract: e16020Background: To compare the difference of genomic and survival of first metastases site between first metastases site of metastatic colorectal cancer (mCRC) in liver and other sites (bone, bra... read more here.
Keywords: metastatic colorectal; mutational profiles; clinical outcomes; colorectal carcinoma ... See more keywords
Whole-Exome Sequencing Reveals Recurrent but Heterogeneous Mutational Profiles in Sporadic WHO Grade 1 Meningiomas
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.740782
Abstract: Human WHO grade 1 meningiomas are generally considered benign tumors; despite this, they account for ≈50% of all recurrent meningiomas. Currently, limited data exist about the mutational profiles of grade 1 meningiomas and patient outcome.… read more here.
Keywords: meningiomas; grade meningiomas; mutational profiles; whole exome ... See more keywords