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Published in 2021 at "Immunity"
DOI: 10.1016/j.immuni.2021.08.022
Abstract: Mutations in the adenosine-to-inosine RNA-editing enzyme ADAR1 p150, including point mutations in the Z-RNA recognition domain Zα, are associated with Aicardi-Goutières syndrome (AGS). Here, we examined the in vivo relevance of ADAR1 binding of Z-RNA. Mutation…
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Keywords:
aicardi gouti;
res syndrome;
rna;
rna binding ... See more keywords