Association of Early-Onset Spasticity and Risk for Cognitive Impairment With Mutations at Amino Acid 499 in SPAST
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Child Neurology"
DOI: 10.1177/0883073818756680
Abstract: Hereditary spastic paraplegia is a phenotypically and genetically heterogeneous group of neurodegenerative disorders characterized by lower extremity weakness and spasticity. Spastic paraplegia 4 (SPG4), caused by heterozygous mutations in the gene SPAST, typically causes a… read more here.
Keywords: mutations amino; early onset; onset spasticity; amino acid ... See more keywords