Abstract A047: ARID1A mutations drive metastasis of pancreatic neuroendocrine tumors and pancreatic adenocarcinomas by activation of NTN1/UNC5B signaling
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.panca2023-a047
Abstract: ARID1A, a component of the SWI/SNF DNA chromatin remodeling complex, is recurrently mutated in many types of cancer. In pancreatic ductal adenocarcinomas (PDACs), mutations in ARID1A are found in 6-15% of cases, and ARID1A expression… read more here.
Keywords: cancer; mutations drive; arid1a mutations; pancreatic neuroendocrine ... See more keywords
Finding the mutations that drive resistance
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DOI: 10.7554/elife.57678
Abstract: Mutations that allow tumors to evolve and become resistant to treatment can be readily identified with a new sequencing approach. read more here.
Keywords: drive resistance; mutations drive; finding mutations;