Disease-associated mutations in Drp1 have fundamentally different effects on the mitochondrial fission machinery.
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DOI: 10.1093/hmg/ddad029
Abstract: Patient mutations have been identified throughout dynamin-related protein 1 (Drp1), the key protein mediator of mitochondrial fission. These changes generally impact young children and often result in severe neurological defects and, in some instances, death.… read more here.
Keywords: associated mutations; fission; mitochondrial fission; mutations drp1 ... See more keywords