Mutations in EPHB4 cause human venous valve aplasia
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DOI: 10.1172/jci.insight.140952
Abstract: Venous valve (VV) failure causes chronic venous insufficiency, but the molecular regulation of valve development is poorly understood. A primary lymphatic anomaly, caused by mutations in the receptor tyrosine kinase EPHB4, was recently described, with… read more here.
Keywords: cause; valve forming; mutations ephb4; valve ... See more keywords