Targeted molecular profiling reveals genetic heterogeneity of poromas and porocarcinomas.
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DOI: 10.1016/j.pathol.2017.10.011
Abstract: The genetic landscape of rare benign tumours and their malignant counterparts is still largely unexplored. While recent work showed that mutant HRAS is present in subsets of poromas and porocarcinomas, a more comprehensive genetic view… read more here.
Keywords: poromas porocarcinomas; mutations found; genetic heterogeneity;
Plasma Sequencing for Patients with GIST—Limitations and Opportunities in an Academic Setting
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DOI: 10.3390/cancers14225496
Abstract: Simple Summary At some point during long-term treatment, gastrointestinal stromal tumors (GIST) stop responding to treatment due to new genetic changes (mutations). These mutations can be found in the blood of patients using very expensive… read more here.
Keywords: academic setting; detection; resistance; blood ... See more keywords