Deleterious Rare Mutations of GLI1 Dysregulate Sonic Hedgehog Signaling in Human Congenital Heart Disease
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DOI: 10.3389/fcvm.2022.798033
Abstract: The Glioma-associated oncogene (Gli) family members of zinc finger DNA-binding proteins are core effectors of Sonic hedgehog (SHH) signaling pathway. Studies in model organisms have identified that the Gli genes play critical roles during organ… read more here.
Keywords: mutations gli1; rare mutations; congenital heart; sonic hedgehog ... See more keywords