OXPHOS Defects Due to mtDNA Mutations: Glutamine to the Rescue!
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DOI: 10.1016/j.cmet.2018.05.010
Abstract: Mutations in mtDNA associated with OXPHOS defects preclude energy harnessing by OXPHOS. The work of Chen et al. (2018) is previewed, reporting flux pathways of glutamine catabolism in mtDNA mutant cells yielding high-energy phosphates through substrate-level… read more here.
Keywords: glutamine rescue; due mtdna; defects due; oxphos defects ... See more keywords