Potentially actionable mutations in intrahepatic cholangiocarcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz413.069
Abstract: Abstract Background Intrahepatic cholangiocarcinoma (iCCA) is a liver neoplasm with few treatment options and a dismal prognosis. To date, the only curative option remains the surgery. New insights concerning its molecular pathogenesis and genetic heterogeneity… read more here.
Keywords: mutations intrahepatic; actionable mutations; intrahepatic cholangiocarcinoma; oncology ... See more keywords
Driver mutations of intrahepatic cholangiocarcinoma shape clinically relevant genomic clusters with distinct molecular features and therapeutic vulnerabilities
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.63417
Abstract: Purpose: To establish a clinically applicable genomic clustering system, we investigated the interactive landscape of driver mutations in intrahepatic cholangiocarcinoma (ICC). Methods: The genomic data of 1481 ICCs from diverse populations was analyzed to investigate… read more here.
Keywords: distinct molecular; intrahepatic cholangiocarcinoma; mutations intrahepatic; mutation ... See more keywords