Mutations in KIRREL1, a slit diaphragm component, cause steroid-resistant nephrotic syndrome.
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DOI: 10.1016/j.kint.2019.06.016
Abstract: Steroid-resistant nephrotic syndrome is a frequent cause of chronic kidney disease almost inevitably progressing to end-stage renal disease. More than 58 monogenic causes of SRNS have been discovered and majority of known steroid-resistant nephrotic syndrome… read more here.
Keywords: slit diaphragm; resistant nephrotic; mutations kirrel1; nephrotic syndrome ... See more keywords