Articles with "mutations kras" as a keyword



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Frequency of somatic mutations in the KRAS gene in patients of the South Russia diagnosed with colorectal cancer.

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Published in 2019 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2019.37.15_suppl.e15081

Abstract: e15081 Background: Colorectal cancer (CRC) is a common pathology in the world; the annual incidence rate reaches 1 million cases, and the annual mortality rate exceeds 500,000. The target therapy of EGFR with monoclonal drugs… read more here.

Keywords: kras gene; somatic mutations; south russia; gene ... See more keywords
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Changes in KRAS mutations in patients with oral mucosa and tongue cancer (OMTC) undergoing medical treatment with cetuximab (Cet).

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Published in 2019 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2019.37.15_suppl.e17524

Abstract: e17524 Background: Mutations in KRAS are known to be predictors of anti-EGFR therapy efficacy. Besides the mutation status of the treatment-naive tumors the changes in the level of mutant DNA during medical treatment are also… read more here.

Keywords: medical treatment; cet; kras exon; treatment ... See more keywords